Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men.

@article{Annerbrink2008CatecholOV,
  title={Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men.},
  author={Kristina Annerbrink and Lars Westberg and Staffan Nilsson and Roland Rosmond and G{\"o}ran Holm and Elias Eriksson},
  journal={Metabolism: clinical and experimental},
  year={2008},
  volume={57 5},
  pages={708-11}
}
Catechol O-methyltransferase (COMT) degrades catecholamines and estrogens, both of which are of known importance for cardiovascular risk factors such as obesity and hypertension. The gene coding for COMT contains a val158-met polymorphism that exerts a considerable influence on enzymatic activity. We hypothesized that this polymorphism might influence risk factors for cardiovascular disease. Deoxyribonucleic acid samples and data regarding blood pressure and anthropometry were collected from… CONTINUE READING

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