Catechol-O-methyltransferase gene polymorphism is associated with risk of psychosis in Alzheimer Disease

@article{Borroni2004CatecholOmethyltransferaseGP,
  title={Catechol-O-methyltransferase gene polymorphism is associated with risk of psychosis in Alzheimer Disease},
  author={Barbara Borroni and Chiara Agosti and Silvana Archetti and Chiara Costanzi and Alessandro Padovani},
  journal={Neuroscience Letters},
  year={2004},
  volume={370},
  pages={127-129}
}
There is emerging evidence that psychosis in Alzheimer Disease (AD) represents a clinically relevant phenotype with a distinct biological process. It has been reported that a functional polymorphism of the catechol-O-methyltransferase (COMT) gene predisposes to an increased risk for schizophrenia and likely to psychosis susceptibility. Aim of this study was to evaluate functional COMT genetic variation as a risk factor for psychosis in Alzheimer Disease. One hundred eighty-one AD patients and… CONTINUE READING

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