Corpus ID: 8629535

Catechins and the treatment of breast cancer: possible utility and mechanistic targets.

@article{Rosengren2003CatechinsAT,
  title={Catechins and the treatment of breast cancer: possible utility and mechanistic targets.},
  author={R. Rosengren},
  journal={IDrugs : the investigational drugs journal},
  year={2003},
  volume={6 11},
  pages={
          1073-8
        }
}
  • R. Rosengren
  • Published 2003
  • Medicine
  • IDrugs : the investigational drugs journal
Breast cancer is a disease that is in need of novel treatment strategies and the use of the catechins epigallocatechin gallate (EGCG), epigallocatechin (EGC) and epicatechin gallate (ECG) is currently being investigated as a potential therapy. The catechins reduce the proliferation of human breast cancer cells in vitro and decrease breast tumor growth in rodents. Furthermore, in vitro studies have demonstrated that the combination of EGCG and tamoxifen is synergistically cytotoxic to ERalpha… Expand

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