Catching the engram: strategies to examine the memory trace

  title={Catching the engram: strategies to examine the memory trace},
  author={Masanori Sakaguchi and Yasunori Hayashi},
  booktitle={Molecular Brain},
Memories are stored within neuronal ensembles in the brain. Modern genetic techniques can be used to not only visualize specific neuronal ensembles that encode memories (e.g., fear, craving) but also to selectively manipulate those neurons. These techniques are now being expanded for the study of various types of memory. In this review, we will summarize the genetic methods used to visualize and manipulate neurons involved in the representation of memory engrams. The methods will help clarify… CONTINUE READING
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