Catatonia and neuroleptic malignant syndrome: psychopathology and pathophysiology
@article{Northoff2002CatatoniaAN, title={Catatonia and neuroleptic malignant syndrome: psychopathology and pathophysiology}, author={Georg Northoff}, journal={Journal of Neural Transmission}, year={2002}, volume={109}, pages={1453-1467} }
Summary.Catatonia was originally described as a psychomotor syndrome in the 19th century by Kahlbaum including motor, affective and behavioral symptoms. Later, at the beginning of the 20th century, catatonia was rather considered as the motoric manifestation of schizophrenia. Accordingly, neuropathological research focused predominantly on those neuroanatomical substrates, i.e. the basal ganglia being primarily involved in the generation of movements. Even though some authors observed minor…
143 Citations
Catatonia and neuroleptic malignant syndrome: two sides of a coin?
- Psychology, MedicineActa neurologica Belgica
- 2007
Five cases of catatonia and NMS are described in order to approach the nosological question of whether the syndrome is to be considered a syndrome with a wide variety of causes and clinical signs or a distinct clinical entity and the clinical similarity between both syndromes.
Catatonia
- Psychology, MedicineCNS Spectrums
- 2016
In DSM-5, catatonia syndrome may be diagnosed as a specifier to major mood disorders, psychotic disorders, general medical conditions, and asCatatonia not otherwise specified, which allows diagnosing the syndrome in a large variety of psychiatric disorders.
Current nosological status, pathomechanism and treatment of catatonia
- Psychology, Medicine
- 2018
In the case of catatonia resistant to benzodiazepines, electroconvulsive therapy (ECT) is effective, and in order to increase the effectiveness of treatment, electro Convulsive therapy and benzidiazepines are used in parallel, which brings satisfactory results.
Catatonía: un síndrome neuropsiquiátrico
- Psychology, Medicine
- 2005
Current concepts of catatonia are reviewed, in reward of historical data, major etiologic causes, neurophysiopathology, diagnostic criteria and treatment, and treatment.
Catatonia: Our current understanding of its diagnosis, treatment and pathophysiology
- Medicine, PsychologyWorld journal of psychiatry
- 2016
Because catatonia is common, highly treatable, and associated with significant morbidity and mortality if left untreated, physicians should maintain a high level of suspicion for this complex clinical syndrome.
Catatonia, Neuroleptic Malignant Syndrome, and Cotard Syndrome in a 22-Year-Old Woman: A Case Report
- Psychology, MedicineCase reports in psychiatry
- 2013
Organic vulnerability to these syndromes, as well as their coexistence and clinical differentiation is discussed in the light of the data observed.
Motor Symptoms and Schizophrenia
- Psychology, MedicineNeuropsychobiology
- 2012
The idea that motor symptoms are closely related to the neurodevelopmental disturbances of schizophrenia and a distinct syndromal dimension with its own pathophysiology is supported.
The Syndrome of Catatonia
- Psychology, MedicineBehavioral sciences
- 2015
Current data supports catatonic syndromes are still common, often severe and of modern clinical importance and it is found that prompt identification and treatment can produce a robust improvement in most cases.
Electroconvulsive therapy in catatonic patients: Efficacy and predictors of response.
- Psychology, MedicineWorld journal of psychiatry
- 2015
Observations are consistent with the hypothesis that ECT is more effective in "top-down" variant of catatonia, in which the psychomotor syndrome may be sustained by a dysregulation of the orbitofrontal cortex, than in "bottom-up" variant, inWhich an extrapyramidal dysregulation may be prevalent.
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