Catastrophic antiphospholipid syndrome with concurrent thrombotic and hemorrhagic manifestations.

@article{Rangel2013CatastrophicAS,
  title={Catastrophic antiphospholipid syndrome with concurrent thrombotic and hemorrhagic manifestations.},
  author={M L M Rangel and I Alghamdi and Gabriel N. Contreras and Timothy Harrington and David J Thomas and Laura M C Barisoni and David N Andrews and Mark G Wolf and Amna Asif and Ali Nayer},
  journal={Lupus},
  year={2013},
  volume={22 8},
  pages={855-64}
}
Antiphospholipid syndrome (APS) is a distinct autoimmune prothrombotic disorder due to pathogenic autoantibodies directed against proteins that bind to phospholipids. APS is characterized by arterial and venous thrombosis and their clinical sequelae. Catastrophic antiphospholipid syndrome (CAPS) is a rare and often fatal form of APS characterized by disseminated intravascular thrombosis and ischemic injury resulting in multiorgan failure. Rarely, intravascular thrombosis in CAPS is accompanied… CONTINUE READING
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