Cataract formation following limited amino acid intake during gestation and lactation.

@article{Bunce1984CataractFF,
  title={Cataract formation following limited amino acid intake during gestation and lactation.},
  author={George E. Bunce and John L. Hess and Daniel Davis},
  journal={Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine},
  year={1984},
  volume={176 4},
  pages={485-9}
}
Female rats were fed defined diets limiting in one or more of certain amino acids and with or without vitamin E throughout gestation and lactation. Deficits of tryptophan, phenylalanine/tyrosine, or methionine/cystine reduced the body weight of progeny to about 50% or less of normal but only low tryptophan was cataractogenic. When total dietary amino acids were 12.4%, a low (65 mg%) level of tryptophan resulted in 34% incidence of cataract if vitamin E was simultaneously withheld. Elevation of… CONTINUE READING