Cataract as a protein condensation disease: the Proctor Lecture.

@article{Benedek1997CataractAA,
  title={Cataract as a protein condensation disease: the Proctor Lecture.},
  author={George B. Benedek},
  journal={Investigative ophthalmology & visual science},
  year={1997},
  volume={38 10},
  pages={1911-21}
}
JL he progression of cataractogenesis in the normal aging population can be characterized as a continual increase in the intensity of light scattered from the lens. This increase is an exponential function of age and has a time constant (A 7") that on average is approximately 35 years. An important molecular mechanism for such light scattering is the condensation of proteins into aggregates. Such aggregated states are also the basic pathogenic factor for a wide class of molecular condensation… CONTINUE READING

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