Catalytic residues and substrate specificity of scytalidoglutamic peptidase, the first member of the eqolisin in family (G1) of peptidases.

@article{Kataoka2005CatalyticRA,
  title={Catalytic residues and substrate specificity of scytalidoglutamic peptidase, the first member of the eqolisin in family (G1) of peptidases.},
  author={Yukiko Kataoka and Katsumi Takada and Hiroshi Oyama and Masahiko Tsunemi and Michael N. G. James and Kohei Oda},
  journal={FEBS letters},
  year={2005},
  volume={579 14},
  pages={2991-4}
}
Scytalidoglutamic peptidase (SGP) is the first-discovered member of the eqolisin family of peptidases with a unique structure and a presumed novel catalytic dyad (E136 and Q53) [Fujinaga et al., PNAS 101 (2004) 3364-3369]. Mutants of SGP, E136A, Q53A, and Q53E lost both the autoprocessing and enzymatic activities of the wild-type enzyme. Coupled with the… CONTINUE READING