Catalytic mechanisms of complex II enzymes: a structural perspective.

@article{Iverson2013CatalyticMO,
  title={Catalytic mechanisms of complex II enzymes: a structural perspective.},
  author={T M Iverson},
  journal={Biochimica et biophysica acta},
  year={2013},
  volume={1827 5},
  pages={648-57}
}
Over a decade has passed since the elucidation of the first X-ray crystal structure of any complex II homolog. In the intervening time, the structures of five additional integral-membrane complex II enzymes and three homologs of the soluble domain have been determined. These structures have provided a framework for the analysis of enzymological studies of complex II superfamily enzymes, and have contributed to detailed proposals for reaction mechanisms at each of the two enzyme active sites… CONTINUE READING
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