Catalase in Leishmaniinae: With me or against me?

  title={Catalase in Leishmaniinae: With me or against me?},
  author={Natalya I. Kraeva and Eva Hor{\'a}kov{\'a} and Alexei Y Kostygov and Luděk Kořen{\'y} and Anzhelika Butenko and Vyacheslav Yurchenko and Julius Luke{\vs}},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
The catalase gene is a virtually ubiquitous component of the eukaryotic genomes. It is also present in the monoxenous (i.e. parasitizing solely insects) trypanosomatids of the subfamily Leishmaniinae, which have acquired the enzyme by horizontal gene transfer from a bacterium. However, as shown here, the catalase gene was secondarily lost from the genomes of all Leishmania sequenced so far. Due to the potentially key regulatory role of hydrogen peroxide in the inter-stagial transformation of… CONTINUE READING
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Infection, Genetics and Evolution

  • N. Kraeva
  • 2017