Catabolic Pathways of Purine Ribonucleotides and Deoxyribonucleotides in Lymphocytes

@article{Cohen1985CatabolicPO,
  title={Catabolic Pathways of Purine Ribonucleotides and Deoxyribonucleotides in Lymphocytes},
  author={A. Cohen and J. Barankiewicz},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1985},
  volume={179},
  pages={437 - 441}
}
  • A. Cohen, J. Barankiewicz
  • Published 1985
  • Biology, Medicine
  • Proceedings of the Society for Experimental Biology and Medicine
  • Abstract Deficiency of either one of the subsequent purine catabolic enzymes adenosine deaminase or purine nucleoside phosphorylase results in immunodeficiency disease in humans. However, the mechanism by which impairment of purine metabolism may cause immunodeficiency is unclear. In the present work we have studied the catabolism of purine ribonucleotides and deoxyribonucleotides in T lymphocytes to better understand the role of purine nucleoside phosphorylase and adenosine deaminase in the… CONTINUE READING
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