Castration differentially regulates nitric oxide synthase in the hypothalamus and pituitary.

@article{Shi1998CastrationDR,
  title={Castration differentially regulates nitric oxide synthase in the hypothalamus and pituitary.},
  author={Qingli Shi and Nancy Lapaglia and Nicholas V. Emanuele and Mary Ann Emanuele},
  journal={Endocrine research},
  year={1998},
  volume={24 1},
  pages={29-54}
}
Mammalian reproductive function is under control of the integrated hypothalamic-pituitary-gonadal (HPG) axis. Castration in male rats has been utilized as an effective tool to investigate hormonal interactions in the mammalian HPG axis. Recently, nitric oxide (NO) has been suggested to play a role in HPG hormonal regulation. In order to gain further insight into the function of the NO-NOS system in reproductive neuroendocrine control, particularly in the gonadal feedback regulation of the… CONTINUE READING