Casticin Potentiates TRAIL-Induced Apoptosis of Gastric Cancer Cells through Endoplasmic Reticulum Stress

@inproceedings{Zhou2013CasticinPT,
  title={Casticin Potentiates TRAIL-Induced Apoptosis of Gastric Cancer Cells through Endoplasmic Reticulum Stress},
  author={Yuan Zhou and Li Tian and Lingzhi Long and Meifang Quan and Fei Liu and Jianguo Cao},
  booktitle={PloS one},
  year={2013}
}
  • Yuan Zhou, Li Tian, +3 authors Jianguo Cao
  • Published in PloS one 2013
  • Biology, Medicine
  • BACKGROUND Casticin is one of the main active components obtained from Fructus Viticis and has been reported to exert anti-carcinogenic activity on a variety of cancer cells but the precise mechanism underlying this activity remains unclear. MATERIALS AND METHODS Apoptotic activities of casticin (1.0 µmol/l) and TRAIL (25, 50 ng/ml) alone or in combination in the gastric cancer cell lines BGC-823, SGC-7901 and MGC-803 were detected by the use of a cell apoptosis ELISA detection kit, flow… CONTINUE READING

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