Cassane- and norcassane-type diterpenes from Caesalpinia crista of Indonesia and their antimalarial activity against the growth of Plasmodium falciparum.

@article{Linn2005CassaneAN,
  title={Cassane- and norcassane-type diterpenes from Caesalpinia crista of Indonesia and their antimalarial activity against the growth of Plasmodium falciparum.},
  author={Thein Zaw Linn and Suresh Awale and Yasuhiro Tezuka and Arjun Hari Banskota and Surya Kant Kalauni and Faisal Attamimi and Jun-ya Ueda and Puji Budi Setia Asih and Din Syafruddin and Ken Tanaka and Shigetoshi Kadota},
  journal={Journal of natural products},
  year={2005},
  volume={68 5},
  pages={706-10}
}
The CH2Cl2 extract of the seed kernels of Caesalpinia crista, which exhibited promising antimalarial activity against Plasmodium berghei-infected mice in vivo, was examined and resulted in the isolation of seven new furanocassane-type diterpenes [caesalpinins C-G (1-5) and norcaesalpinins D and E (6, 7)] together with norcaesalpinins A-C (8-10) and 11 known compounds (norcaesalpinins A-C, 2-acetoxy-3-deacetoxycaesaldekarin e, caesalmin B, caesaldekarin e, caesalpin F, 14(17)-dehydrocaesalpin F… CONTINUE READING

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