Caspofungin Etest endpoint for Aspergillus isolates shows poor agreement with the reference minimum effective concentration.

@article{Fuller2010CaspofunginEE,
  title={Caspofungin Etest endpoint for Aspergillus isolates shows poor agreement with the reference minimum effective concentration.},
  author={Jeff Fuller and Adam Schofield and Safeer Jiwa and Crystal Sand and B. R. H. Jansen and R. Mark Rennie},
  journal={Journal of clinical microbiology},
  year={2010},
  volume={48 2},
  pages={479-82}
}
The Clinical and Laboratory Standards Institute (CLSI) M38-A2 reference broth microdilution (BMD) method for the antifungal susceptibility testing of filamentous fungi now includes guidelines for testing echinocandin activity using the minimum effective concentration (MEC) as the endpoint measurement. In this study, we compared the caspofungin Etest MIC on RPMI agar and Mueller-Hinton agar (supplemented with glucose and methylene blue [MGM]) to the BMD MEC for 345 clinical Aspergillus isolates… CONTINUE READING