Caspases: key mediators of apoptosis.

  title={Caspases: key mediators of apoptosis.},
  author={Nancy A. Thornberry},
  journal={Chemistry & biology},
  volume={5 5},
Recent studies have established that members of the caspase protease family are essential components of a conserved cell death program. Insights into their biological roles, structure and mechanism are enabling investigators to begin to explore the therapeutic potential of caspase inhibition. 

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