Caspase activity during cell stasis: avoidance of apoptosis in an invertebrate extremophile, Artemia franciscana.

@article{Menze2007CaspaseAD,
  title={Caspase activity during cell stasis: avoidance of apoptosis in an invertebrate extremophile, Artemia franciscana.},
  author={Michael A. Menze and Steven C. Hand},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2007},
  volume={292 5},
  pages={
          R2039-47
        }
}
  • M. Menze, S. Hand
  • Published 1 May 2007
  • Biology
  • American journal of physiology. Regulatory, integrative and comparative physiology
Evaluation of apoptotic processes downstream of the mitochondrion reveals caspase-9- and low levels of caspase-3-like activities in partly purified extracts of Artemia franciscana embryos. However, in contrast to experiments with extracts of human hepatoma cells, cytochrome c fails to activate caspase-3 or -9 in extracts from A. franciscana. Furthermore, caspase-9 activity is sensitive to exogenous calcium. The addition of 5 mM calcium leads to a 4.86 +/- 0.19 fold (SD) (n = 3) increase in… 
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Methods Citations
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