Caspase 8 expression and signaling in Fas injury-resistant human fetal astrocytes.

@article{Wosik2001Caspase8E,
  title={Caspase 8 expression and signaling in Fas injury-resistant human fetal astrocytes.},
  author={Karolina Wosik and Burkhard Becher and A Ezman and Jos{\'e}phine Nalbantoglu and Jack P. Antel},
  journal={Glia},
  year={2001},
  volume={33 3},
  pages={217-24}
}
Fas (APO-1/CD95) is a cell surface receptor initially identified in lymphoid cells, but more recently detected in the central nervous system under pathological, usually inflammatory, conditions. In most Fas expressing cells, triggering of Fas by its ligand or by antagonistic antibodies leads to apoptosis. Human fetal astrocytes (HFA) constitutively express… CONTINUE READING