Caspase 8 differentially controls hepatocytes and non-parenchymal liver cells during chronic cholestatic liver injury in mice.

@article{Chaudhary2013Caspase8D,
  title={Caspase 8 differentially controls hepatocytes and non-parenchymal liver cells during chronic cholestatic liver injury in mice.},
  author={Kunal Chaudhary and Christian Liedtke and Svenja Wertenbruch and Christian Trautwein and Konrad L. Streetz},
  journal={Journal of hepatology},
  year={2013},
  volume={59 6},
  pages={1292-8}
}
BACKGROUND & AIMS Receptor mediated cell death through the activation of caspases has been identified as an important mechanism to control life and death in various tissues and is thus crucial for the maintenance of liver tissue homeostasis. Here we investigated how caspase 8 (Casp8) differentially regulates immune-mediated liver injury and regeneration in… CONTINUE READING