Caspase 3 is involved in the apoptosis induced by triptolide in HK-2 cells.

@article{Shu2009Caspase3I,
  title={Caspase 3 is involved in the apoptosis induced by triptolide in HK-2 cells.},
  author={Bin Shu and Weigang Duan and Jincheng Yao and Jingfeng Huang and Zhen-zhou Jiang and Lu-yong Zhang},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2009},
  volume={23 4},
  pages={598-602}
}
Triptolide, a main active component extracted from the traditional Chinese herbal medicine, Tripterygium wilfordii Hook. f (TWHf), has been shown to possess potent immunosuppressive and anti-inflammatory properties. However, the toxicity of triptolide limits its clinical applications. Here we treated the human proximal tubular epithelial cell line HK-2… CONTINUE READING