Caspase 3 from rock bream (Oplegnathus fasciatus): genomic characterization and transcriptional profiling upon bacterial and viral inductions.

@article{Elvitigala2012Caspase3F,
  title={Caspase 3 from rock bream (Oplegnathus fasciatus): genomic characterization and transcriptional profiling upon bacterial and viral inductions.},
  author={Don Anushka Sandaruwan Elvitigala and Ilson Whang and H. K. A. Premachandra and Navaneethaiyer Umasuthan and Myung-Joo Oh and Sung-Ju Jung and Sang-Yeob Yeo and B. Lim and Jeong-Ho Lee and H C Park and Jehee Lee},
  journal={Fish & shellfish immunology},
  year={2012},
  volume={33 1},
  pages={99-110}
}
Caspase 3 is a prominent mediator of apoptosis and participates in the cell death signaling cascade. In this study, caspase 3 was identified (Rbcasp3) and characterized from rock bream (Oplegnathus fasciatus). The full-length cDNA of Rbcasp3 is 2683 bp and contains an open reading frame of 849 bp, which encodes a 283 amino acid protein with a calculated molecular mass of 31.2 kDa and isoelectric point of 6.31. The amino acid sequence resembles the conventional caspase 3 domain architecture… CONTINUE READING
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