Caspase-3 and prostaglandins signal for tumor regrowth in cancer therapy


Chemo- and radio-therapeutic regimens frequently kill cancer cells by inducing apoptosis, a cell-death subroutine that involves the activation of a particular class of proteases called caspases. In a recent issue of Nature Medicine, Huang et al. (2011) show that caspase activation in dying tumor cells causes the release of soluble lipid messengers, notably… (More)
DOI: 10.1038/onc.2011.459


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