Casitas B lineage lymphoma b is a key regulator of peripheral tolerance in systemic lupus erythematosus.


OBJECTIVE To analyze whether the expression and modulation of T cell receptor (TCR) signaling is dependent on Casitas B lineage lymphoma b (Cbl-b) in T cells from patients with systemic lupus erythematosus (SLE) upon stimulation with a tolerogenic substance. METHODS Peripheral blood mononuclear cells were obtained from 20 patients with SLE (active disease… (More)
DOI: 10.1002/art.37833


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