• DOI:10.1136/vr.153.7.202
Corpus ID: 19788587

Cases of scrapie with unusual features in Norway and designation of a new type, Nor98

@article{Benestad2003CasesOS,
  title={Cases of scrapie with unusual features in Norway and designation of a new type, Nor98},
  author={S. Benestad and P. Sarradin and B. Thu and J. Sch{\"o}nheit and M. Tranulis and B. Bratberg},
  journal={Veterinary Record},
  year={2003},
  volume={153},
  pages={202 - 208}
}

• S. Benestad, P. Sarradin, +3 authors B. Bratberg
• Published 2003
• Medicine, Biology
• Veterinary Record

Five cases of scrapie with unusual features have been diagnosed in Norway since 1998. The affected sheep showed neurological signs dominated by ataxia, and had the PrP genotypes homozygous A136 H154 Q171/ A136 H154 Q171 or heterozygous A136 HI54Q171/A136 R154 Q171, which are rarely associated with scrapie. Brain histopathology revealed neuropil vacuolisation essentially in the cerebellar and cerebral cortices; vacuolation was less prominent in the brainstem, and no lesions were observed at the… Expand

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