Cases and Observations connected with Disease of the Pancreas and Duodenum.

@article{BrightCasesAO,
  title={Cases and Observations connected with Disease of the Pancreas and Duodenum.},
  author={Richard Bright},
  journal={Medico-chirurgical transactions},
  volume={18 Pt 1},
  pages={
          1-56
        }
}
  • R. Bright
  • Medicine
  • Medico-chirurgical transactions
40 Citations
Diabetes and Pancreatic Cancer—A Dangerous Liaison Relying on Carbonyl Stress
TLDR
The findings suggest that carbonyl stress is involved in cancer development and growth and may be the mechanistic link between diabetes and pancreatic cancer, thus representing a potential drug target and the potential use ofcarbonyl-scavenging agents and AGE inhibitors in PDAC prevention and treatment, particularly in high-risk diabetic individuals.
Understanding the Contribution of Insulin Resistance to the Risk of Pancreatic Cancer.
TLDR
It is shown that the presence of insulin resistance independently increases pancreatic cancer mortality even in individuals without diabetes and hyperglycemia.
An integrative theory for cancer (Review)
  • G. Luo, Na Liu
  • Biology
    International journal of molecular medicine
  • 2019
TLDR
The integrative theory views cancer in an integrative manner and proposes that both genetic alterations and tumor-host interaction as regards metabolism and immunology determine the destiny of the tumor and host.
Diabetes and Pancreatic Cancer: A Bidirectional Relationship Perspective
TLDR
An attempt was made to understand the bidirectional causal relationship between diabetes mellitus and pancreatic cancer and metformin, an antidiabetic and antineoplastic drug, is reported to reduce the risk of pancreatic cancers and should be considered as first-line therapy in new-onset diabetes patients.
Exploring the link between diabetes and pancreatic cancer
TLDR
The markedly increased risk of pancreatic cancer in patients with new-onset diabetes compared with long-standing diabetes observed in several epidemiological studies indicates a complex and bidirectional connection.
A Historical Overview of Diabetic Nephropathy
TLDR
The availability of kidney biopsy and refinements in the quantification of albuminuria were instrumental in defining the course and prevalence of what was then termed diabetic nephropathy.
PANCREATIC CANCER IN THE WORLD: AN EPIDEMIOLOGICAL REVIEW
TLDR
The incidence and mortality of pancreatic cancer in developed countries is higher than developing countries, and its incidence and death rates are rising gradually.
Pancreatic Cancer: Historical Problem as well as Personal and Current Solutions which have Prospects in Translational Medicine
TLDR
It is concluded that its replication would lead to obtaining the breakthrough as regards developing that target therapy which could conduce to cancer cure, this being inclusive of the pancreas.
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