Casein kinase II phosphorylates the neural cell adhesion molecule L1.

@article{Wong1996CaseinKI,
  title={Casein kinase II phosphorylates the neural cell adhesion molecule L1.},
  author={Eric V. Wong and Andrew W. Schaefer and G. C. Landreth and Vance P. Lemmon},
  journal={Journal of neurochemistry},
  year={1996},
  volume={66 2},
  pages={
          779-86
        }
}
L1 is an axonal cell adhesion molecule found primarily on projection axons of both the CNS and PNS. It is a phosphorylated membrane-spanning glycoprotein that can be immunoprecipitated from rat brain membranes in association with protein kinase activities. Western blot analysis demonstrates that casein kinase II (CKII), a ubiquitous serine/threonine kinase enriched in brain, is present in these immunoprecipitates. CKII preparations partially purified from PC12 cells are able to phosphorylate… CONTINUE READING
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