Casein kinase II and protein kinase C modulate hepatitis delta virus RNA replication but not empty viral particle assembly.

@article{Yeh1996CaseinKI,
  title={Casein kinase II and protein kinase C modulate hepatitis delta virus RNA replication but not empty viral particle assembly.},
  author={T S Yeh and Szecheng J. Lo and P. J. Chen and Yong Hee Lee},
  journal={Journal of virology},
  year={1996},
  volume={70 9},
  pages={6190-8}
}
Hepatitis delta virus (HDV) contains two virus-specific delta antigens (HDAgs), large and small forms, which are identical in sequence except that the large one contains 19 extra amino acids at the C terminus. HDAgs are nuclear phosphoproteins with distinct biological functions; the small form activates HDV RNA replication, whereas the large form suppresses this process but is required for viral particle assembly. In this study, we have characterized the phosphorylative property of HDAg in a… CONTINUE READING

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