Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction

@article{Davidson2005CaseinK1,
  title={Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction},
  author={Gary Davidson and Wei Wu and Jinlong Shen and Josipa Bili{\'c} and Ursula Fenger and Peter Stannek and Andrei Glinka and Christof Niehrs},
  journal={Nature},
  year={2005},
  volume={438},
  pages={867-872}
}
Signalling by Wnt proteins (Wingless in Drosophila) has diverse roles during embryonic development and in adults, and is implicated in human diseases, including cancer. LDL-receptor-related proteins 5 and 6 (LRP5 and LRP6; Arrow in Drosophila) are key receptors required for transmission of Wnt/β-catenin signalling in metazoa. Although the role of these… CONTINUE READING