Casein Kinase II: an attractive target for anti-cancer drug design.


Casein Kinase II (CK2) is a ubiquitous serine/threonine kinase that is highly conserved in eukaryotic cells. CK2 has been shown to impact cell growth and proliferation, as numerous growth-related proteins are substrates of CK2. More importantly, experimental evidence linking increased expression and activity of CK2 to human cancers underscores the relevance… (More)
DOI: 10.1016/j.biocel.2010.06.010


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