Case series: Slowing alpha rhythm in late-stage ALS patients

@article{Hohmann2018CaseSS,
  title={Case series: Slowing alpha rhythm in late-stage ALS patients},
  author={M. Hohmann and T. Fomina and V. Jayaram and Theresa Emde and J. Just and M. Synofzik and B. Sch{\"o}lkopf and L. Sch{\"o}ls and M. Grosse-Wentrup},
  journal={Clinical Neurophysiology},
  year={2018},
  volume={129},
  pages={406-408}
}
The alpha peak frequency (APF) of the human electroencephalogram (EEG) is a reliable neurophysiological marker for cognitive abilities. In these case series, we document a shift of the APF towards the lower end of the EEG spectrum in two completely locked-in ALS patients. In not completely locked-in ALS patients, the alpha rhythm lies within the common frequency range. We discuss potential implications of this shift for the largely unknown cognitive state of completely locked-in ALS patients. 
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