Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS)

Abstract

Post-transplant distal limb bone marrow edema syndrome or calcineurin inhibitor-induced pain syndrome (CIPS) is generally a self-limiting but debilitating acute pain syndrome that has been reported in 2–14 % of renal transplant recipients. The disease is extensively described in the transplant literature in patients receiving the calcineurin inhibitors cyclosporine and tacrolimus. We present a case of CIPS arising in a patient 73 days after renal allograft, review the imaging findings, and discuss proposed etiologies and differential diagnoses. To the authors’ knowledge, CIPS has not been characterized as a distinct entity in the radiology literature.

DOI: 10.1007/s00256-013-1616-5

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@article{Chapin2013CaseRI, title={Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS)}, author={Russell W. Chapin and Elizabeth L. Chua and Jennifer C Simmons and Martin Bunke}, journal={Skeletal Radiology}, year={2013}, volume={42}, pages={1311-1315} }