Case report: detection of rotavirus RNA in the cerebrospinal fluid of a child with rotavirus gastroenteritis and meningism.

@article{Medici2011CaseRD,
  title={Case report: detection of rotavirus RNA in the cerebrospinal fluid of a child with rotavirus gastroenteritis and meningism.},
  author={Maria Cristina Medici and Laura Anna Abelli and Paola Guerra and Icilio Dodi and G. Dettori and Carlo Chezzi},
  journal={Journal of medical virology},
  year={2011},
  volume={83 9},
  pages={1637-40}
}
Although case reports have described detection of rotavirus (RV) in extraintestinal sites such as the liver, kidney, and central nervous system (CNS) of children with RV gastroenteritis, CNS localization in RV infection seems to be rare. RT-PCR and nucleotide sequencing detected a G1P[8] strain in the stool and cerebrospinal fluid (CSF) samples of a patient with concurrent RV-associated enteritis and CNS signs. Upon sequence analysis, the viruses detected in the CSF was identical to the virus… CONTINUE READING