Case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review

  title={Case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review},
  author={K. G. Brurberg and M. S. F{\o}nhus and L. Larun and S. Flottorp and K. Malterud},
  journal={BMJ Open},
  • K. G. Brurberg, M. S. Fønhus, +2 authors K. Malterud
  • Published 2014
  • Medicine
  • BMJ Open
  • Objective To identify case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), and explore how the validity of case definitions can be evaluated in the absence of a reference standard. Design Systematic review. Setting International. Participants A literature search, updated as of November 2013, led to the identification of 20 case definitions and inclusion of 38 validation studies. Primary and secondary outcome measure Validation studies were assessed for risk of bias… CONTINUE READING
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