Case-control study of the muscular compartments and osseous strength in neurofibromatosis type 1 using peripheral quantitative computed tomography.

@article{Stevenson2005CasecontrolSO,
  title={Case-control study of the muscular compartments and osseous strength in neurofibromatosis type 1 using peripheral quantitative computed tomography.},
  author={David A. Stevenson and Laurie J. Moyer-Mileur and John C Carey and Jody L Quick and Charles J Hoff and David Viskochil},
  journal={Journal of musculoskeletal & neuronal interactions},
  year={2005},
  volume={5 2},
  pages={145-9}
}
Skeletal anomalies are observed in neurofibromatosis type 1 (NF1), but the pathogenesis is unknown. Given that muscle mass is important in the development of the strength of bone, peripheral quantitative computed tomography (pQCT) was utilized to compare measurements of muscle compartments between NF1 individuals and controls. Forty individuals with NF1 (age 5-18 years) were evaluated. Cross-sectional measurements, at the 66% tibial site, were obtained using pQCT (XCT-2000, Stratec) and… CONTINUE READING
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