Case-control study of human papillomavirus and oropharyngeal cancer.

  title={Case-control study of human papillomavirus and oropharyngeal cancer.},
  author={G. D'Souza and A. Kreimer and R. Viscidi and M. Pawlita and C. Fakhry and W. Koch and W. Westra and M. Gillison},
  journal={The New England journal of medicine},
  volume={356 19},
  • G. D'Souza, A. Kreimer, +5 authors M. Gillison
  • Published 2007
  • Medicine
  • The New England journal of medicine
  • BACKGROUND Substantial molecular evidence suggests a role for human papillomavirus (HPV) in the pathogenesis of oropharyngeal squamous-cell carcinoma, but epidemiologic data have been inconsistent. METHODS We performed a hospital-based, case-control study of 100 patients with newly diagnosed oropharyngeal cancer and 200 control patients without cancer to evaluate associations between HPV infection and oropharyngeal cancer. Multivariate logistic-regression models were used for case-control… CONTINUE READING
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