Case Report: Electronic Screening Improves Efficiency in Clinical Trial Recruitment

@article{Thadani2009CaseRE,
  title={Case Report: Electronic Screening Improves Efficiency in Clinical Trial Recruitment},
  author={Samir R. Thadani and Chunhua Weng and J. Thomas Bigger and John F. Ennever and David Wajngurt},
  journal={Journal of the American Medical Informatics Association : JAMIA},
  year={2009},
  volume={16 6},
  pages={
          869-73
        }
}
This study evaluated the performance of an electronic screening (E-screening) method and used it to recruit patients for the NIH sponsored ACCORD trial. Out of the 193 E-screened patients, 125 met the age criterion ("age>or=40"). For all of these 125 patients, the performance of E-screening was compared with investigator review. E-screening achieved a negative predictive accuracy of 100% (95% CI: 98-100%), a positive predictive accuracy of 13% (95% CI: 6-13%), a sensitivity of 100% (95% CI: 45… CONTINUE READING

Tables, Results, and Topics from this paper.

Key Quantitative Results

  • The method maximized the use of a patient database query (i.e., excluded ineligible patients with a 100% accuracy and automatically assembled patient information to facilitate manual review of only patients who were classified as "potentially eligible" by E-screening) and significantly reduced the screening burden associated with the ACCORD trial.
  • The method maximized the use of a patient database query (i.e., excluded ineligible patients with a 100% accuracy and automatically assembled patient information to facilitate manual review of only patients who were classified as “potentially eligible” by E-screening) and significantly reduced the screening burden associated with the ACCORD trial.

Citations

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