Case Report: An Autopsy Case of Malignant Mesothelioma with Osseous and Cartilaginous Differentiation (Bone Morphogenetic Protein-2 in Mesothelial Cells and Its Tumor)

@article{Kiyozuka1999CaseRA,
  title={Case Report: An Autopsy Case of Malignant Mesothelioma with Osseous and Cartilaginous Differentiation (Bone Morphogenetic Protein-2 in Mesothelial Cells and Its Tumor)},
  author={Yasuhiko Kiyozuka and H. Miyazaki and Katsuhiko Yoshizawa and Hideto Senzaki and Daigo Yamamoto and Kyoichi Inoue and Kazuhisa Bessho and Yasunori Okubo and Kenji Kusumoto and Airo Tsubura},
  journal={Digestive Diseases and Sciences},
  year={1999},
  volume={44},
  pages={1626-1631}
}
An autopsy case of biphasic malignant mesothelioma with osseous and cartilaginous differentiation diffusely involving the peritoneal cavity was confirmed by light microscopic histochemistry, immunohistochemistry, and electron microscopy. A reverse transcription-polymerase chain reaction using specific primers for bone morphogenetic protein-2 (BMP-2) revealed weak positive transcript in normal mesothelial cells and up-regulated expression around bone-forming malignant mesothelioma tissue… CONTINUE READING
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