Cascade Models of Synaptically Stored Memories

@article{Fusi2005CascadeMO,
  title={Cascade Models of Synaptically Stored Memories},
  author={S. Fusi and P. Drew and L. Abbott},
  journal={Neuron},
  year={2005},
  volume={45},
  pages={599-611}
}
  • S. Fusi, P. Drew, L. Abbott
  • Published 2005
  • Psychology, Medicine
  • Neuron
  • Storing memories of ongoing, everyday experiences requires a high degree of plasticity, but retaining these memories demands protection against changes induced by further activity and experience. Models in which memories are stored through switch-like transitions in synaptic efficacy are good at storing but bad at retaining memories if these transitions are likely, and they are poor at storage but good at retention if they are unlikely. We construct and study a model in which each synapse has a… CONTINUE READING
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    References

    SHOWING 1-10 OF 123 REFERENCES
    All-or-none potentiation at CA3-CA1 synapses.
    • 307
    • PDF
    A synaptic model of memory: long-term potentiation in the hippocampus
    • 10,422
    • PDF
    Learning in Neural Networks with Material Synapses
    • 271
    • PDF
    Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus
    • 268
    • PDF
    NMDA receptor antagonists sustain LTP and spatial memory: active processes mediate LTP decay
    • 173
    • PDF
    Dissociable stages of human memory consolidation and reconsolidation
    • 892
    • PDF