Carvedilol modifies antioxidant status of patients with stable angina

  title={Carvedilol modifies antioxidant status of patients with stable angina},
  author={Jan Kowalski and Maciej Banach and Marcin Barylski and Robert Irzmański and Lucjan Pawlicki},
  journal={Cellular & Molecular Biology Letters},
The aim of this study was to evaluate the effect of carvedilol on the enzymatic antioxidative defence and plasma antioxidative activity in patients with stable angina. The study comprised 30 patients, aged 37–49 years with stable angina. Patients received carvedilol in escalating doses of 12.5 mg/24 h, 25 mg/24 h, and 50 mg/24 h for 4 weeks each. The control group was matched for age and gender, and consisted of 12 healthy volunteers, aged 39-49 years. Blood samples were collected from the… CONTINUE READING