Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.

@article{Bhardwaj2017CarvedilolDT,
  title={Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial.},
  author={Ankit Bhardwaj and Chandan Kumar Kedarisetty and Chitranshu Vashishtha and Ajeet Singh Bhadoria and Ankur Jindal and G. Naveen Vital Kumar and Ashok Choudhary and Saggere Muralikrishna Shasthry and Rakhi Maiwall and Manoj Kumar and Vikram Bhatia and Shiv Kumar Sarin},
  journal={Gut},
  year={2017},
  volume={66 10},
  pages={
          1838-1843
        }
}

• Ankit Bhardwaj, Chandan Kumar Kedarisetty, +9 authors Shiv Kumar Sarin
• Published 2017 in Gut
• DOI:10.1136/gutjnl-2016-311735

BACKGROUND AND AIMS Carvedilol is effective in the primary prophylaxis for large oesophageal varices. We investigated its use in preventing progression of small to large oesophageal varices. METHODS Consecutive cirrhotics with small oesophageal varices were prospectively randomised to either carvedilol (n=70) or placebo (n=70) and followed up for a minimum of 24 months. Endoscopy was done at baseline and six monthly intervals. Hepatic vein pressure gradient (HVPG) was measured at baseline and… CONTINUE READING

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