Carvedilol and adrenergic agonists suppress the lipopolysaccharide-induced NO production in RAW 264.7 macrophages via the adrenergic receptors.

@article{Pekarov2009CarvedilolAA,
  title={Carvedilol and adrenergic agonists suppress the lipopolysaccharide-induced NO production in RAW 264.7 macrophages via the adrenergic receptors.},
  author={Michaela Pekarov{\'a} and Jana Kr{\'a}lov{\'a} and Luk{\'a}{\vs} Kubala and Milan C{\'i}z and Ivana Pape{\vz}{\'i}kov{\'a} and Tatiana Ma{\vc}i{\vc}kov{\'a} and Jana Pe{\vc}ivov{\'a} and Radom{\'i}r Nos{\'a}ľ and Anton{\'i}n Lojek},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2009},
  volume={60 1},
  pages={143-50}
}
The interaction of adrenergic agonists and/or antagonists with the adrenergic receptors expressed on immunologically active cells including macrophages plays an important role in regulation of inflammatory responses. Our study investigated the effects of carvedilol, a unique vasodilating beta-adrenergic antagonist, and endogenous adrenergic agonists (adrenalin, noradrenalin, and dopamine) and/or antagonists (prazosin, atenolol) on lipopolysaccharide-stimulated nitric oxide (NO) production from… CONTINUE READING

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Effect of carvedilol on the production of reactive 149 oxygen species by HL-60 cells

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