Cartilage type IX collagen-proteoglycan contains a large amino-terminal globular domain encoded by multiple exons.

@article{Vasios1988CartilageTI,
  title={Cartilage type IX collagen-proteoglycan contains a large amino-terminal globular domain encoded by multiple exons.},
  author={George Vasios and Ikuko Nishimura and Hiroshi Konomi and Michel van der Rest and Yoshifumi Ninomiya and Bjorn Reino Olsen},
  journal={The Journal of biological chemistry},
  year={1988},
  volume={263 5},
  pages={2324-9}
}
Type IX collagen in cartilage consists of molecules composed of three genetically distinct polypeptide subunits. One of the subunits, alpha 2(IX), contains a covalently attached glycosaminoglycan side chain whereas a second subunit, alpha 1(IX), contains a large noncollagenous, amino-terminal domain called NC4. In this report, we describe for the first time the complete primary structure of this noncollagenous domain, based on cloning and sequencing of cDNA and genomic DNA as well as amino acid… CONTINUE READING

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