Cartilage disorders: potential therapeutic use of mesenchymal stem cells.

  title={Cartilage disorders: potential therapeutic use of mesenchymal stem cells.},
  author={Anna Spagnoli and Lara Longobardi and Lynda O'rear},
  journal={Endocrine development},
Chondrogenesis is a well-orchestrated process driven by chondroprogenitors that undergo to condensation, proliferation and chondrocyte differentiation. Because cartilage lacks regenerative ability, treatments for cartilage diseases are primarily palliative. Adult bone marrow contains a reservoir of mesenchymal stem cells (MSC) with in vitro and in vivo potential of becoming cartilage. To optimize the potential therapeutic use of MSC in cartilage disorders, we need to understand the mechanisms… CONTINUE READING
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