Cartilage degeneration in post-collapse cases of osteonecrosis of the human femoral head: altered mechanical properties in tension, compression, and shear.

@article{Magnussen2005CartilageDI,
  title={Cartilage degeneration in post-collapse cases of osteonecrosis of the human femoral head: altered mechanical properties in tension, compression, and shear.},
  author={Robert A. Magnussen and Farshid Guilak and Thomas Parker Vail},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2005},
  volume={23 3},
  pages={576-83}
}
Osteonecrosis, or avascular necrosis, is a painful and debilitating condition characterized by progressive joint degeneration subsequent to collapse of necrotic regions of trabecular bone. A clear understanding of the mechanism of cartilage degeneration in osteonecrosis is critical to the development of treatment strategies aimed at sparing the femoral head. An analysis of 13 post-collapse osteonecrotic (ON) human femoral heads was performed relative to 24 non-ON controls to determine… CONTINUE READING

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