Cartilage damage in osteoarthritis and rheumatoid arthritis—two unequal siblings

  title={Cartilage damage in osteoarthritis and rheumatoid arthritis—two unequal siblings},
  author={Thomas Pap and Adelheid Korb-Pap},
  journal={Nature Reviews Rheumatology},
Cartilage damage is a key feature of degenerative joint disorders—primarily osteoarthritis (OA)—and chronic inflammatory joint diseases, such as rheumatoid arthritis (RA). Substantial progress has been made towards understanding the mechanisms that lead to degradation of the cartilage matrix in either condition, which ultimately results in the progressive remodelling of affected joints. The available data have shown that the molecular steps in cartilage matrix breakdown overlap in OA and RA… CONTINUE READING
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