Depth dependence of the mechanical and osmotic properties of cartilage
- C. Silva, I. Horkayne-Szakaly, +5 authors F. Horkay
- In Gels and Biomedical Materials (Eds. F. Horkay…
Cartilage is a complex biological tissue that exhibits gel-like behavior. Its primary biological function is providing compressive resistance to external loading and nearly frictionless lubrication of joints. In this study, we model cartilage extracellular matrix using a biomimetic system. We demonstrate that poly(vinyl) alcohol (PVA) hydrogels are robust biomaterials exhibiting mechanical and swelling properties similar to that of cartilage extracellular matrix. A comparison is made between the macroscopic behavior of PVA gels and literature data reported for cartilage.