Carteolol Hydrochloride Protects Human Corneal Epithelial Cells From UVB-Induced Damage In Vitro

  title={Carteolol Hydrochloride Protects Human Corneal Epithelial Cells From UVB-Induced Damage In Vitro},
  author={Keiichi Kuwahara and Nobuyuki Oizumi and Shigeki Fujisawa and Masaki Tanito and Akihiro Ohira},
Purpose: To investigate whether carteolol hydrochloride has protective effects against ultraviolet B (UVB)-induced damage in human corneal epithelial cells (HCECs). Methods: Cultured HCECs were exposed to a single dose of UVB 300 mJ/cm2, and the cell viability was measured 12 hours after the UVB irradiation using a cell-counting kit. Test samples at 0.01-1.0 mmol/L (carteolol hydrochloride, timolol maleate, betaxolol hydrochloride, levobunolol hydrochloride, or nipradilol) were added to the… 

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