Carrier-enhanced human growth hormone absorption across isolated rabbit intestinal tissue.

@article{Mlynek2000CarrierenhancedHG,
  title={Carrier-enhanced human growth hormone absorption across isolated rabbit intestinal tissue.},
  author={G M Mlynek and Leonor Calvo and Joseph R. Robinson},
  journal={International journal of pharmaceutics},
  year={2000},
  volume={197 1-2},
  pages={13-21}
}
Small molecular weight alpha acid derivatives are able to enhance the intestinal absorption of human growth hormone through isolated rabbit intestinal tissue. The enhancement is not through the usual tissue modification associated with traditional penetration enhancers nor is it through an active transport process. Rather these small molecules associate with human growth hormone in solution to make it more transportable through intestinal tissue. It is shown that the enhancer has specificity… CONTINUE READING