Carrageenan based hydrogels for drug delivery, tissue engineering and wound healing.

  title={Carrageenan based hydrogels for drug delivery, tissue engineering and wound healing.},
  author={Ramanathan Yegappan and Vignesh Selvaprithiviraj and Sivashanmugam Amirthalingam and Rangasamy Jayakumar},
  journal={Carbohydrate polymers},

Recent Advances in Chemically-Modified and Hybrid Carrageenan-Based Platforms for Drug Delivery, Wound Healing, and Tissue Engineering

This work aims to overview the recent advances in various chemical modification approaches and hybrid carrageenan-based platforms for tissue engineering and drug delivery applications and formation of hybrid platforms with significant mechanical, chemical and biological properties.

Polysaccharide-based hydrogels: New insights and futuristic prospects in wound healing.

Marine Algae Polysaccharides as Basis for Wound Dressings, Drug Delivery, and Tissue Engineering: A Review

The present review considers the physicochemical and biological properties of polysaccharides from brown, red, and green algae used in the latest technologies of regenerative medicine (tissue engineering, modulation of the drug delivery system, and the design of wound dressing materials).

Current Understanding of Hydrogel for Drug Release and Tissue Engineering

The characteristics and crosslinking methods of natural and synthetic hydrogels are introduced and the design and principle of intelligent hydrogel used for drug release and tissue engineering are highlighted.

New Insights of Scaffolds Based on Hydrogels in Tissue Engineering

This study’s main purpose is to establish the main properties needed to develop sustainable polymeric scaffolds that can be applied in tissue engineering to improve the tissue regeneration process without producing other side effects to the environment.

Recent Advances in Natural Gum-Based Biomaterials for Tissue Engineering and Regenerative Medicine: A Review

The origin and physico-chemical characteristics of potentially used natural gums are reviewed and various forms of scaffolds based on gums and their efficacy in 3D cell culture and various tissue regenerations such as bone, osteoarthritis and cartilage, skin/wound, retinal, neural, and other tissues are discussed.

Carrageenan: Drug Delivery Systems and Other Biomedical Applications

A review of recent research on the various types of carrageenan-based biomedical and pharmaceutical applications is provided.



Cell delivery systems using alginate--carrageenan hydrogel beads and fibers for regenerative medicine applications.

The present work was focused on the development and characterization of new hydrogel systems based on natural origin polymers, namely, alginate and carrageenan, into different formats and with

Enzymatic and ionic crosslinked gelatin/K-carrageenan IPN hydrogels as potential biomaterials

The mechanical strength increased with an increase in carrageenan content while swelling ratio and degradability decreased correspondingly, and the IPN hydrogels were shown to support adhesion and proliferation of L929 cell line.

Photocrosslinkable Kappa‐Carrageenan Hydrogels for Tissue Engineering Applications

This is the first study reporting the synthesis of photocrosslinkable κ‐CA with controllable compressive moduli, swelling ratios and pore size distributions, thus enabling the development of cell‐material platforms that can be applied and tailored to a broad range of tissue engineering strategies.

Cyclic β-(1→3) (1→6) glucan/carrageenan hydrogels for wound healing applications

The presence of CBG in the hydrogel enhanced the wound healing ability both in vitro in cells as well as in vivo in rats, suggesting that the CBG/Car hydrogels have the potential to be developed as a novel wound dressing material.

Carrageenan-based hydrogels for the controlled delivery of PDGF-BB in bone tissue engineering applications.

Kappa-carrageenan, a naturally occurring polymer, was used to develop hydrogel beads with the ability to incorporate GFs with the purpose of establishing an effective angiogenesis mechanism, and the results demonstrate the achievement of an efficient encapsulation and controlled release profile matching those usually required for the development of a fully functional vascular network.

Self-assembled carbohydrate hydrogels for prolonged pain management

  • R. KamelH. Abbas
  • Materials Science
    Pharmaceutical development and technology
  • 2013
P2 hydrogel composed of chitosan-carrageenan (1-1) PEC attained the most compromised rheological shear-thinning thixotropic behavior, good bioadhesive properties, and the most retarded release and permeation with an f2 value <50 compared to chitOSan hydrogels, altogether with non-irritancy to the skin.